منابع مشابه
One-pot native chemical ligation of peptide hydrazides enables total synthesis of modified histones.
One of the rising demands in the field of protein chemical synthesis is the development of facile strategies that yield the protein in workable quantities and homogeneity, with fewer handling steps. Although the native chemical ligation of peptide hydrazides has recently been shown to be useful for the chemical synthesis of proteins carrying acid-sensitive modification groups, previous hydrazid...
متن کاملPot economy and one-pot synthesis
The one-pot synthesis of a target molecule in the same reaction vessel is widely considered to be an efficient approach in synthetic organic chemistry. In this review, the characteristics and limitations of various one-pot syntheses of biologically active molecules are explained, primarily involving organocatalytic methods as key tactics. Besides catalysis, the pot-economy concepts presented he...
متن کاملOne-pot Synthesis of Polysubstituted Indolizine Derivatives
An efficient approach to the synthesis of 1,2,3-trisubstituted indolizines is described via one-pot reactions of pyridine and dialkyl acetylendicarboxylate in the presence of ethyl 2-chloroacetoacetate in MeOH at room temperature. The corresponding 1, 2, 3-trisubstituted indolizines may be useful building blocks for the construction of complex indolizine derivatives.
متن کاملA Modified-One Pot Synthesis of Diaminoglyoxime
The one pot reaction of glyoxal and hydroxylamine hydrochloride in aqueous sodium hydroxide was found to be a safe and inexpensive method for the preparation of diaminoglyoxime. By increasing stoichiometric ratio of the hydroxylamine hydrochloride and decreasing the solvent volume, the product yield increased considerably (~ 70%).
متن کاملOne-pot synthesis of (−)-Ambrox
(-)-Ambrox is recognised as the prototype of all ambergris odorants. Widely used in perfumery, (-)-Ambrox is an important ingredient due to its unique scent and excellent fixative function. An environmentally friendly and practical preparation of (-)-Ambrox is still unavailable at present although a lot of attention has been paid to this hot research topic for many years. A one-pot synthesis of...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2001
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.0002.904